Dietary Dialium guineense stem-bark supplementation improves growth performance and haemato-biochemical characteristics of broiler chickens.

Poultry farmers, particularly in developing countries, are concerned about the rising cost of conventional feed additives such as antibiotics. This has sparked a lot of interest in the search for phytogenic feed additives (PFAs) that can be used as alternative to antibiotic growth promoter in chicken diets. Thus, the purpose of this study was to evaluate the chemical composition of Dialium guineensestem-bark (DGSB) one of such PFAs, and its effect of its supplementation on the performance of Ross 308 broiler chickens. Fresh D. guineense stem barks were manually harvested, dried on shade and thereafter milled into DGSB powder. The DGSB was chemically analysed and standard broiler chicken diets were supplemented with DGSB at 0 (T1), 0.5 (T2), 1.0 (T3) and 1.5 (T4) g kg-1 feed. 200 day-old chicks were raised on starter mash from days 1-21 and finisher mash from days 22-47. Results suggested that DGSB is relatively high in fibre, ash and important phytochemicals. Average daily feed intake (ADFI) responded to incremental levels of DGSB linearly. Maximum ADFI was achieved at 1.5 g DGSB/kg feed. Birds in group T2 recorded the lowest feed conversion ratio (FCR) of 1.90, while those in group T4 had the highest FCR of 2.68. Broiler chickens on 0.5 g/kg feed attained higher (P < 0.05) final live weight (FLW) and average daily gain (ADG). Results indicated that dietary DGSB supplementation influenced aspects of the blood traits of Ross 308 broiler chickens. Results also show that DGSB had a quadratic effect on FLW, ADG, aspects of red blood cell indices, platelets, white blood cells, lymphocytes, glucose, cholesterol, alanine transaminase (ALT) and aspartate transaminase (AST) in broiler chickens. In conclusion, DGSB is high in fibre, ash and some beneficial phytochemicals and may be incorporated to broiler chicken nutrition at a supplementation level not beyond 0.5 g/kg feed for best growth performance and blood characteristics.

Meta-analysis of the influence of dietary cassava on productive indices and egg quality of laying hens.

There are an increasing number of studies on the effect of cassava (Manihot esculenta Crantz) on performance of laying hens with inconsistent outcomes. This study, therefore, used a meta-analytic approach to examine the effect of cassava-based diets on feed intake (FI), feed conversion ratio (FCR) end production data such as hen day egg production (HDEP), egg weight (EW), egg mass (EM), Haugh unit (HU), shell weight (SW) and shell thickness (ST) in laying hens. Two hundred and three studies were identified in a search performed in PubMed, Scopus and Google Scholar databases of which thirteen studies were suitable for the meta-analysis. Subgroup and meta-regression analyses were performed to explore the responses of laying hens to dietary cassava and sources of heterogeneity, respectively using the following moderators: study continent, cassava type, cassava processing methods, inclusion level, layer strain, feeding durations, number of layers and hen's age. Data were pooled using a random-effects model and statistical analyses were performed in OpenMEE software. Results show that cassava increased FI (mean difference MD = 0.97 g/d; 95% confidence intervals (CI) 0.05, 1.90) and reduced egg weight (MD = -0.72 g; 95% CI -1.26, -0.19) and SW (MD = -0.11 g; 95% CI -0.18, -0.04) when compared to control. Laying hens fed cassava diets had HDEP, FCR, EM, ST and HU values that compared favourably with the controls. Subgroup analysis demonstrated that inclusion of cassava at ≤ 25% in layer diets had no deleterious effects on measured outcomes taking cognizance of significant heterogeneity. However, meta-regression results showed that most of the sources of heterogeneity were explained by the studied moderators. In conclusion, ≤25% of cassava (CRM and CPM) can be included in layer diets without adverse effects on feed intake, feed conversion ratio and egg production characteristics, indicating that cassava has a very bright future as an energy source in the diets of laying hens.

Meta-analysis of Saccharomyces cerevisiae on enhancement of growth performance, rumen fermentation and haemato-biochemical characteristics of growing goats.

The use of Saccharomyces cerevisiae (SC) feed additives to improve animal performance are on the increase; however, the results of the action of SC supplementation on goats performance indices are conflicting. Thus, the thrust of this meta-analysis was to examine the influence of dietary SC intervention on the growth performance, haemato-biochemical indices and ruminal fermentation characteristics of growing goats fed total mixed ration (TMR). The search conducted in Google Scholar, PubMed and Scopus databases using several keywords yielded 500 studies of which 16 full-text articles were utilised for study. Response variables were aggregated via a random-effects model. The results showed that goats fed SC experienced higher average daily gain (ADG) than the controls (as standardized mean difference, SMD = 2.14; 95% confidence interval, CI: 1.40 to 2.89). In converse, dietary SC intervention had a small impact on dry matter intake (DMI) and feed conversion ratio (FCR). Subgroup analysis demonstrated that SC type (active vs inactive) improved FCR and ADG in growing goats. Results suggested that SC preparation increased blood glucose, white blood cell (WBC), ruminal propionate and total volatile fatty acid levels. There is heterogeneity among the articles used in the study, and aspects of studied covariates explained the variation. In conclusion, this study indicated that dietary yeast can positively influence growth performance, haemato-biochemical indices, and rumen fermentation parameters of growing goats.

Corrigendum: Meta-analytic effect of Saccharomyces cerevisiae on dry matter intake, milk yield and components of lactating goats.

[This corrects the article DOI: 10.3389/fvets.2022.1014977.].

Potentials of Dietary Zinc Supplementation in Improving Growth Performance, Health Status, and Meat Quality of Broiler Chickens.

The demand for chicken meat is on the rise, necessitating high level of production and efficient feed conversion which to a certain extent can be actualized by the use of specific trace minerals like zinc (Zn). Zn is a part of several enzymes involved in the metabolism of protein, fat, carbohydrates, and nucleic acids. In addition, Zn has antioxidant properties and is vital for hormone function, including growth, pancreatic, and sex hormones. Its deficiency in animals is characterized by poor fertility, decreased feed intake, poor growth, testicular atrophy, and weakened immunity. Nano-Zn sources have been shown to be more bioavailable than conventional zinc (organic and inorganic) sources. Zn from organic sources, on the other hand, has higher bioavailability than Zn from inorganic sources. Furthermore, Zn supplementation promotes growth, enhances antioxidant capacity, modulates the immunity, and improves health indices in broiler chickens. Published studies have demonstrated that Zn supplementation has the potential to improve carcass yield and meat quality in broilers with various research contradictions. However, a clear understanding of the role of Zn in broiler nutrition is still lacking, necessitating further research. As a result, the purpose of this review was to highlight the influence of Zn (organic or inorganic) supplementation on growth, blood characteristics, antioxidant status, immune responses, Zn tissue/fecal concentrations, intestinal villus histomorphology, and meat quality of broiler chickens as well as Zn bioavailability to understand the role of Zn in broiler nutrition, resolve contradictory research results, and identify knowledge gaps. Understanding the role of dietary Zn in broiler chicken nutrition and meat quality will avail important suggestion on policy advancements and sustainable use of Zn in the broiler chicken industry.

Meta-analytic effect of Saccharomyces cerevisiae on dry matter intake, milk yield and components of lactating goats.

The results of investigations on the impact of Saccharomyces cerevisiae (SC) on performance characteristics of lactating goats are inconsistent. Thus, this study aimed to summarize available evidence on the effect of SC supplementation on dry matter intake (DMI), milk yield and composition in lactating goats using meta-analysis. A systematic search performed on Scopus, Google Scholar and PubMed databases yielded 1,368 studies of which 18 were used for the meta-analysis. Subgroup and meta-regression analyses were performed to explore the sources of heterogeneity in response to dietary SC supplementation. A random-effects model showed that SC had a moderate effect on milk yield [standardized mean differences (SMD) = 0.51; 95% CI: 0.20 to 0.82, p = 0.001] and milk fat (SMD = 0.30; 95% CI: 0.05 to 0.55, p = 0.02) in lactating goats when compared to the controls. Subgroup analysis by SC type indicated that live SC had a large to moderate effect on milk yield (SMD = 1.46; 95% CI: 0.96 to 1.96, p < 0.001) and milk fat (SMD = 0.51; 95% CI: 0.19 to 0.84, p = 0.002), whereas dead SC had a large negative effect on DMI (SMD = -0.82; 95% CI: -1.28 to -0.7, p < 0.001) and a moderate reduction effect on milk yield (SMD = -0.55; 95% CI: -0.99 to -1.96, p = 0.015). We found significant heterogeneity across studies that evaluated the effect of SC treatment on DMI and milk yield in lactating goats and meta-regression analysis explained most of the sources of heterogeneity. In conclusion, pooled results showed that dietary SC supplementation increased milk yield and fat in lactating goats. In addition, subgroup analysis revealed that both live and fermented SC increased milk yield and fat in lactating goats, while dead SC reduced DMI and milk yield.

Meta-analysis of substitution value of maize with cassava (Manihot esculenta Cratnz) on growth performance of broiler chickens.

There are variable results on the effect of cassava on the performance characteristics of broiler chickens. As a result, this meta-analysis was performed to determine the effect of cassava on feed intake, feed conversion ratio (FCR), and average daily gain (ADG) in broiler chickens. A methodical search performed on Google Scholar, Scopus, Web of Science, and PubMed databases as well as individual journals yielded 365 published articles. Out of 365 studies, 23 that met the inclusion criteria were used for the meta-analysis. Outcome measures were pooled using a random-effects model. Results were expressed as standardized mean differences (SMD) at 95% confidence intervals (CIs). Subgroup and meta-regression analyses were used to explore the effects of studied covariates (broiler strain, inclusion level of cassava, number of broilers per replicate, cassava processing methods, and cassava form) on measured outcomes. Results indicated that cassava had a small positive effect on feed intake (SMD = -0.07, 95% CI -0.26, 0.12) and FCR (SMD = 0.14; 95% CI 0.82, 1.746), but a large negative effect on ADG (SMD = -1.67; 95% CI -1.99, -1.35) compared to the controls. Subgroup analysis by cassava form showed that wet fermented cassava peel meal (WFCPM) had a moderate impact on feed intake (SMD = 0.62, 95% CI 0.47, 0.77) and ADG (SMD = 0.66, 95% CI 0.37, 0.95) in broiler chickens compared with the controls. Our results also found improved growth performance in broiler chickens fed cassava at 4-10%. There is evidence of between-study variance, and studied covariates explain most of the sources of heterogeneity. This study concluded that the replacement of maize with 4-10% WFCPM improved growth performance traits in broiler chickens.

Meta-analysis of Zinc Supplementation on Laying Performance, Egg Quality Characteristics, and Blood Zinc Concentrations in Laying Hens.

There are inconsistent results on the influence of zinc (Zn) supplementation levels on productive indices of laying hens. This study, therefore, uses meta-analysis to synthesis evidence on the effect of inclusion of Zn in chicken diets on performance, egg quality, and blood Zn status of laying hens. Eleven studies were identified and used to analyze the effect of diets with or without Zn supplementation on feed intake, feed conversion ratio (FCR), hen day egg production (HDEP), egg weight (EW), egg mass (EM), Haugh unit (HU) scores, eggshell thickness (EST), eggshell weight (ESW), and blood Zn concentrations in laying hens. Data extracted from the 11 studies included in the meta-analysis were pooled using a random-effects model and expressed as standardized mean differences (SMDs) at a 95% confidence interval (CI). Results indicate that dietary Zn supplementation reduced FCR (SMD = - 0.50 g feed/g egg; 95% CI: - 0.68 to - 0.31) and increased HDEP (SMD = 0.33%; 95% CI: 0.18 to 0.48), EW (SMD = 0.14 g; 95% CI: 0.03 to 0.25) and EM (SMD = 0.58 g/hen/day; 95% CI: 0.22 to 0.95), HU (SMD = 0.64; 95% CI: 0.42 to 0.85), EST (SMD = 0.84 mm; 95% CI: 0.45 to 1.23), and plasma Zn concentration (SMD = 4.20 mg/dl; 95% CI: 2.99 to 5.40) compared with the controls. In contrast, feed intake and ESW were not significantly different from controls. Restricted subgroup analysis indicated that chosen moderators (age of hen, inclusion level, chicken breed/strain, and supplementation duration) influenced the results of this meta-analysis. There was evidence of significant heterogeneity, and meta-regression indicated that moderators explained most of the sources of heterogeneity. We conclude that dietary zinc supplementation had positive effect on feed conversion ratio, laying performance, aspects of egg quality traits, and blood zinc concentrations in laying hens. The findings from this meta-analysis will help in policy advancements and sustainable use of zinc in the egg production industry.